Effects of Propofol and Midazolam on the Inflammation of Lungs after Intravenous Endotoxin Administration in Rats | Zendy

Mine Çelik | Zendy; Ayten Saraçoğlu | Zendy; Tolga Saracoglu | Zendy; Hüsnü Kürşad | Zendy; Ayşenur Dostbil | Zendy; Mehmet Aksoy | Zendy; Ali Ahişkalıoğlu | Zendy; İlker İnce | Zendy

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Effects of Propofol and Midazolam on the Inflammation of Lungs after Intravenous Endotoxin Administration in Rats

Author(s) -

Mine Çelik,

Ayten Saraçoğlu,

Tolga Saracoglu,

Hüsnü Kürşad,

Ayşenur Dostbil,

Mehmet Aksoy,

Ali Ahişkalıoğlu,

İlker İnce

Publication year - 2014

Publication title -

eurasian journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.337

H-Index - 13

eISSN - 1308-8742

pISSN - 1308-8734

DOI - 10.5152/eajm.2014.70

Subject(s) - medicine , propofol , midazolam , anesthesia , bolus (digestion) , ards , sepsis , sedation , lung

Pulmonary complications are important sepsis (such as ARDS, diffuse pneumonia). Acute respiratory distress syndrome (ARDS) is characterized by the extensive migration of neutrophils into alveoli of the lungs. Propofol and midazolam are the most widely used agents for sedation in intensive care units. Aimed to investigate the effects of anaesthesia with propofol and midazolam on measured hemodynamic variables and neutrophil migration induced by Escherichia Coli endotoxin (ECE) in pulmonary viscera.

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