Comparison of the Mycobacterium Growth Indicator Tube Method and the Method of Proportion for Drug Susceptibility Testing of Mycobacterium Tuberculosis | Zendy

Ayşe Aktaş | Zendy; Nimet Yiğit | Zendy; Ahmet Ayyıldız | Zendy; Ayşe BAŞTOPÇU | Zendy

Open Access

Comparison of the Mycobacterium Growth Indicator Tube Method and the Method of Proportion for Drug Susceptibility Testing of Mycobacterium Tuberculosis

Author(s) -

Ayşe Aktaş,

Nimet Yiğit,

Ahmet Ayyıldız,

Ayşe BAŞTOPÇU

Publication year - 2014

Publication title -

eurasian journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.337

H-Index - 13

eISSN - 1308-8742

pISSN - 1308-8734

DOI - 10.5152/eajm.2014.23

Subject(s) - medicine , ethambutol , isoniazid , sputum , tuberculosis , mycobacterium tuberculosis , streptomycin , drug resistance , rifampicin , microbiology and biotechnology , antibiotics , pathology , biology

Tuberculosis is an important public health problem in developed and, especially, developing countries. The incidence of multi-drug-resistant Mycobacterium tuberculosis (MDR-TB) has increased in recent years. Mycobacterial culture and susceptibility testing must be rapidly concluded for effective treatment and control of the disease. The present study evaluated the reliability of the Mycobacterium Growth Indicator Tube (MGIT) method for testing the susceptibility of M. tuberculosis to four first-line antimicrobial drugs by comparing MGIT results to those obtained by the method of proportion (MOP), which served as the reference method.

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