Metabolic Syndrome and Neurotrophins: Effects of Metformin and Non-Steroidal Antiinflammatory Drug Treatment | Zendy

Mariyana G. Hristova | Zendy

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Metabolic Syndrome and Neurotrophins: Effects of Metformin and Non-Steroidal Antiinflammatory Drug Treatment

Author(s) -

Mariyana G. Hristova

Publication year - 2011

Publication title -

eurasian journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.337

H-Index - 13

eISSN - 1308-8742

pISSN - 1308-8734

DOI - 10.5152/eajm.2011.32

Subject(s) - metformin , medicine , nerve growth factor , dyslipidemia , neurotrophin , endocrinology , brain derived neurotrophic factor , metabolic syndrome , neurotrophic factors , pharmacology , obesity , diabetes mellitus , receptor

Metabolic syndrome (MS) presents with central obesity, impaired glucose metabolism, dyslipidemia and hypertension. Our aim was to examine the effect of metformin treatment either alone or in combination with non-steroidal anti-inflammatory drugs (NSAID) on plasma levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in patients with early stage MS (MS-es) and generalized MS (MS-ge).

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