Evidence for diverse prognosis in high-grade serous ovarian carcinoma: solid, pseudoendometrioid, and transitional-like; so-called “set morphology” and progesterone receptor status
Author(s) -
Halit Üner,
Metin Demir,
Dinçer Göksülük,
Ayşe Kars,
Meral Üner,
Alp Usubütün
Publication year - 2022
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2022.01571
Subject(s) - serous carcinoma , serous fluid , immunohistochemistry , ovarian carcinoma , pathology , oncology , medicine , biology , cystadenocarcinoma , survival analysis , ovarian cancer , cancer
High-grade serous ovarian carcinoma (HGSC) is one of the major tumors of the gynecological system with a poor survival rate and variable microscopic appearance. It was suggested that SET (solid, pseudo-endometrioid and transitional-like) morphology in ovarian HGSC is predictably associated with BRCA deficiencies. In this study, we investigated the microscopic patterns and some immunohistochemical markers predicting the prognosis of serous carcinoma.
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