The place and prognostic value of tert promoter mutation in molecular classification in grade ii-iii glial tumors and primary glioblastomas | Zendy

Neslihan Kaya Terzi | Zendy; İsmail Yılmaz | Zendy; Büğe Öz | Zendy

Open Access

The place and prognostic value of tert promoter mutation in molecular classification in grade ii-iii glial tumors and primary glioblastomas

Author(s) -

Neslihan Kaya Terzi,

İsmail Yılmaz,

Büğe Öz

Publication year - 2021

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2021.01555

Subject(s) - atrx , idh1 , sanger sequencing , isocitrate dehydrogenase , telomerase reverse transcriptase , biology , glioma , telomerase , oligodendroglioma , cancer research , mutation , astrocytoma , promoter , immunohistochemistry , idh2 , gene , oncology , medicine , genetics , gene expression , biochemistry , enzyme

Diffuse gliomas, the most common primary malignant brain tumors, have been classified by the World Health Organization as class II-IV gliomas. After 2016, two mutations in the promoter region of the telomerase reverse transcriptase (TERT) gene were identified in addition to the IDH, 1p / 19q, and ATRX status.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research