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Pleomorphic adenoma of breast: report of two cases, one in a male patient
Author(s) -
Orwa Elaiwy,
Khaled Al-sawalmeh,
Hayan Abo Samra,
Abdulrazzaq Haider,
Mohammed Akhtar
Publication year - 2021
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2021.01543
Subject(s) - myoepithelial cell , medicine , pleomorphic adenoma , immunohistochemistry , histology , malignant transformation , pathology , adenoma , radiology , salivary gland
Pleomorphic adenoma of breast (PAB) is a rare mammary tumor of a mixed epithelial-myoepithelial nature. We report two patients with PAB, one of which is male. We believe our male patient is the sixth case of PAB in male breast in the literature. The two cases expressed heterogeneous clinical and radiological characteristics while showing similar histology and immunohistochemical staining profile. The first case was managed with surgical resection while the second underwent interventional radiology excision. PAB is usually a benign entity with occasional cases of recurrence. Malignant transformation is rare but has been reported in a few cases.

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