Efficiency of cytology samples for pd-l1 evaluation and comparison with tissue samples
Author(s) -
İbrahim Kulaç,
Asli Aydin,
Pınar Bulutay,
Pınar Fırat
Publication year - 2020
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2020.01494
Subject(s) - medicine , cytology , lung cancer , biopsy , cancer , pd l1 , pathology , immunohistochemistry , significant difference , oncology , immunotherapy
Lung cancer is the leading cause of cancer-related death. PD-L1 blockers have become a first-line option for advanced non-small cell lung cancer (NSCLC) patients. Guidelines require the assessment of PD-L1 expression by immunohistochemistry. Although tissue samples are widely used, cytologic samples could be an alternative. In this study, we compared cytologic samples with tissue samples for PD-L1 evaluation in NSCLC cases.
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