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Case series of hemophagocytic lymphohistiocytosis from a tertiary care centre: an underdiagnosed entity
Author(s) -
Vijay Kumar,
Bhavna Sharma,
Abhay S Nigam
Publication year - 2019
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2018.01456
Subject(s) - hemophagocytic lymphohistiocytosis , medicine , tertiary care , bone marrow aspirate , bone marrow , pediatrics , retrospective cohort study , disease , surgery , pathology
Hemophagocytic Lymphohistiocytosis (HLH) is an uncommon, life-threatening hyperinflammatory syndrome, caused by severe hypercytokinemia, due to an overstimulated but ineffective immune process. The presenting features of HLH are non-specific, mimicking many other diseases, and hence its early recognition still remains a challenge. It requires a high index of suspicion and detailed analysis of clinical and laboratory findings to arrive at a conclusive diagnosis. The objective of this study is to present detailed clinical and laboratory features of a series of HLH cases.

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