Proliferation marker (ki67) in sub-categorization of neuroendocrine tumours of the lung
Author(s) -
Rashi Garg,
Amanjit Bal,
Ashim Das,
Navneet Singh,
Harkant Singh
Publication year - 2018
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2018.01436
Subject(s) - neuroendocrine tumors , small cell lung carcinoma , pathology , neuroendocrine differentiation , carcinoid tumors , lymphovascular invasion , carcinoma , small cell carcinoma , medicine , lung , carcinoid tumour , immunohistochemistry , ki 67 , proliferation index , cancer , metastasis , prostate cancer
The 2015 WHO classification classifies neuroendocrine tumours (NET) of the lung into typical carcinoid, atypical carcinoid, large cell neuroendocrine carcinoma and small cell carcinoma based on morphology alone. Mitosis is the major parameter for this classification, and thus several studies have focused on the role of Ki67 in these tumours but without conclusive results. The aim of the study was to categorize neuroendocrine tumours of the lung based on morphology and to assess the utility of Ki67 in diagnosis.
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