The role of cd34 and d2-40 in the differentiation of dermatofibroma and dermatofibrosarcoma protuberans | Zendy

Canan Sadullahoğlu | Zendy; Yelda Dere | Zendy; Turkan Rezanko Atasever | Zendy; Mine Tunakan Oztop | Zendy; Önder Karaaslan | Zendy

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The role of cd34 and d2-40 in the differentiation of dermatofibroma and dermatofibrosarcoma protuberans

Author(s) -

Canan Sadullahoğlu,

Yelda Dere,

Turkan Rezanko Atasever,

Mine Tunakan Oztop,

Önder Karaaslan

Publication year - 2017

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2017.01402

Subject(s) - dermatofibrosarcoma protuberans , cd34 , dermatofibroma , immunohistochemistry , pathology , dermatofibrosarcoma , atypia , nuclear atypia , medicine , biology , stem cell , genetics

Dermatofibroma (DF) is a benign fibrohistiocytic tumor whereas dermatofibrosarcoma protuberans (DFSP) has intermediate malignant potential. CD34 is the most commonly used antibody in differentiating these tumors. Various studies have stated the rates of D2-40 expression as 0-50% in DFSPs and 86-100% in DFs. Our aim in this study was to determine the expression of CD34 and D2-40 in DFs and DFSPs and the possible use of D2-40 in the differential diagnosis of these lesions.

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