Are cd68 and factor viii-ra expression different in central and peripheral giant cell granuloma of jaw: an immunohistochemical comparative study | Zendy

Soudabeh Sargolzaei | Zendy; Nasim Taghavi | Zendy; Farzaneh Poursafar | Zendy

Open Access

Are cd68 and factor viii-ra expression different in central and peripheral giant cell granuloma of jaw: an immunohistochemical comparative study

Author(s) -

Soudabeh Sargolzaei,

Nasim Taghavi,

Farzaneh Poursafar

Publication year - 2013

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2017.01401

Subject(s) - giant cell , cd68 , pathology , central giant cell granuloma , granuloma , peripheral blood mononuclear cell , medicine , immunohistochemistry , biology , in vitro , biochemistry

Central giant cell granuloma and peripheral giant cell granuloma of the jaw and oral cavity are identical in histopathologic features, although they are different in pathogenesis and clinical behavior. The aim of present study was to compare CD 68 and factor VIII related antigen (VIII-RA ) immunoreactivity in central giant cell granuloma and peripheral giant cell granuloma to determine the biologic nature and clinical behavior of these lesions which may lead to a better or new treatment modality.

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