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Tert expression in pituitary adenomas
Author(s) -
Nuray Can,
Mehmet Çelik,
Buket Yılmaz Bülbül,
Necdet Süt,
Filiz Özyılmaz,
Semra Aytürk,
Sibel Güldiken,
Nurtaç Sarıkaş,
Fulya Öz Puyan,
Tülin Yalta,
Ali Kutlu
Publication year - 2017
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2016.01387
Subject(s) - immunohistochemistry , pathology , pituitary adenoma , pituitary gland , adenoma , cytoplasm , medicine , biology , hormone , biochemistry
Although pituitary adenomas have benign histomorphological features, some of them may present in an aggressive manner. To predict the behaviour of these tumours, telomerase reverse transcriptase (TERT) activity in pituitary adenomas has been the subject of a few studies with contradictory results. This study aims to investigate whether immunohistochemical expression of TERT differs in neoplastic and nonneoplastic pituitary tissues and aims to investigate whether TERT expression is related to clinicopathological features of pituitary adenomas.

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