Expression of monomeric c-reactive protein in infarcted brain tissue from patients with alzheimerÂ’s disease | Zendy

Mark Slevin | Zendy; Donghui Liu | Zendy; Glenn Ferris | Zendy; Malik Al-hsinawi | Zendy; Raid Saleem Al-Baradie | Zendy; Jerzy Krupiński | Zendy

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Expression of monomeric c-reactive protein in infarcted brain tissue from patients with alzheimerÂ’s disease

Author(s) -

Mark Slevin,

Donghui Liu,

Glenn Ferris,

Malik Al-hsinawi,

Raid Saleem Al-Baradie,

Jerzy Krupiński

Publication year - 2016

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2016.01374

Subject(s) - neurodegeneration , parenchyma , pathology , inflammation , stroke (engine) , immunohistochemistry , medicine , chemistry , disease , mechanical engineering , engineering

We have previously shown that monomeric-C-reactive protein is deposited in significant quantities within the brain parenchyma after stroke. Since we have recently identified a possible role of this protein in supporting neurodegeneration and aberrant vascular development we identified a small group of post-mortem brain samples from individuals who had Alzheimer's disease and evidence of tissue infarction/ micro-infarction on histological examination.

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