Metastasis-associated protein 1 expression in oral squamous cell carcinomas: correlation with metastasis and angiogenesis | Zendy

Azadeh AndishehTadbir | Zendy; Ali Dehghani Nazhvani | Zendy; Soheil Pardis | Zendy; Zohreh JaafariAshkavandi | Zendy; Mohammad Javad Ashraf | Zendy; Bijan Khademi | Zendy; Fereshteh Kamali | Zendy

Open Access

Metastasis-associated protein 1 expression in oral squamous cell carcinomas: correlation with metastasis and angiogenesis

Author(s) -

Azadeh AndishehTadbir,

Ali Dehghani Nazhvani,

Soheil Pardis,

Zohreh JaafariAshkavandi,

Mohammad Javad Ashraf,

Bijan Khademi,

Fereshteh Kamali

Publication year - 2014

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2014.01277

Subject(s) - angiogenesis , metastasis , immunohistochemistry , cancer research , medicine , pathology , cell , basal cell , tumor progression , carcinoma , cancer , biology , oncology , genetics

Metastasis-associated protein 1 (MTA1) has been associated with poor prognosis in several carcinomas. Recent investigation has found that in different tumors, MTA1 protein significantly correlates with tumor angiogenesis, suggesting that MTA1 may be a possible angiogenesis-promoting molecule in malignant tumors. Thus, the current study was performed to determine the role of MTA1 protein in the biological behavior of oral squamous cell carcinoma and its relation with tumor angiogenesis.

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