Ttf-1 may not be a reliable marker for differentiating metastasis from brain tumors | Zendy

Betül Ünal | Zendy; Şenay Yıldırım | Zendy; Cem Sezer | Zendy; Dinç Süren | Zendy

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Ttf-1 may not be a reliable marker for differentiating metastasis from brain tumors

Author(s) -

Betül Ünal,

Şenay Yıldırım,

Cem Sezer,

Dinç Süren

Publication year - 2013

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2014.01261

Subject(s) - pathology , immunohistochemistry , medulloblastoma , staining , schwannoma , clone (java method) , pathological , metastasis , brain tumor , medicine , biology , cancer , dna , genetics

TTF-1 is widely used as an immunohistochemical marker of lung and thyroid tumors. However, TTF-1 expression has been described in tumors from other sites. The presence of TTF-1 expression in primary brain tumors is largely unclear and has not been clearly specified yet. We characterized expression of two TTF-1 clones in primary brain tumors with relevance to tumor types and grades.

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