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Morphological aspects and distribution of interstitial cells of cajal in the human upper urinary tract
Author(s) -
Radu-alexandru Prisca,
Andrada Loghin,
Horea-gheorghe gozAR,
Cosmin Moldovan,
Tekla Mosó,
Zolta Derzsi,
Angela Borda
Publication year - 2014
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2014.01242
Subject(s) - interstitial cell of cajal , interstitial cell , pathology , urinary system , anatomy , ureter , biology , cd117 , chemistry , immunohistochemistry , medicine , microbiology and biotechnology , urology , stem cell , cd34
The mechanism by which the ureter propels urine towards the bladder has a myogenic origin, through peristaltic contractions. This pyeloureteral autorhythmicity is generated by specialized, electrically active cells, the interstitial cells of Cajal, located in the proximal regions of the upper urinary tract. The aim of this study was to describe the exact location and the distribution of interstitial Cajal cells in the human upper urinary tract and to analyze their normal number and morphology. This is a preliminary study, which will allow the study of these cells in different urinary tract pathologies.

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