Assessment of maturation status of tumor-infiltrating dendritic cells in invasive ductal carcinoma of the breast: relation with vascular endothelial growth factor expression | Zendy

N. Deeb | Zendy; Radwa A. Mehanna | Zendy

Open Access

Assessment of maturation status of tumor-infiltrating dendritic cells in invasive ductal carcinoma of the breast: relation with vascular endothelial growth factor expression

Author(s) -

N. Deeb,

Radwa A. Mehanna

Publication year - 2013

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2013.01186

Subject(s) - dendritic cell , vascular endothelial growth factor , biology , progesterone receptor , estrogen receptor , follicular dendritic cells , angiogenesis , cancer research , pathology , immune system , breast cancer , medicine , cancer , immunology , antigen presenting cell , t cell , vegf receptors , genetics

Poor immunogenicity has been described in breast carcinoma although dendritic cells, the major antigen presenters, are known to infiltrate the tumor. Vascular endothelial growth factor has been proposed to reduce local immune response in tumors. We investigated the maturation status of dendritic cells in invasive ductal carcinoma of the breast in relation to vascular endothelial growth factor expression and clinicopathological parameters.

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