The Selective Expression of Ret Finger Protein in Endometrial Cancer: Can RFP be a Marker of Serous Carcinomas?
Author(s) -
Gaye Güler Tezel,
Zehra Ordulu,
Çiğdem Himmetoğlu,
Alp Usubütün
Publication year - 2012
Publication title -
turkish journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.305
H-Index - 14
eISSN - 1309-5730
pISSN - 1018-5615
DOI - 10.5146/tjpath.2012.01127
Subject(s) - serous fluid , endometrial cancer , medicine , endometrium , serous carcinoma , carcinoma , pathology , endometrial hyperplasia , atypical hyperplasia , malignancy , carcinogenesis , ovarian cancer , cancer , cancer research , oncology
Endometrial cancer is a common malignancy of the gynecological system and has been classified into two major groups, Types I and II. Type I tumors are estrogen-related, low-grade endometrioid tumors, whereas type II tumors are aggressive, high-grade non-endometrioid tumors. Ret finger protein is a nuclear transcription factor with a tripartite motif that is highly expressed in different tumor cells.
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