Sarcomatoid chromophobe renal cell carcinoma with osteosarcoma-like differentiation which presented as a retroperitoneal mass: a case report | Zendy

Ayşegül Sarı | Zendy; Gözde Evcim | Zendy; Murat Ermete | Zendy; Serhat Gür | Zendy

Open Access

Sarcomatoid chromophobe renal cell carcinoma with osteosarcoma-like differentiation which presented as a retroperitoneal mass: a case report

Author(s) -

Ayşegül Sarı,

Gözde Evcim,

Murat Ermete,

Serhat Gür

Publication year - 2011

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2011.01068

Subject(s) - chromophobe cell , rhabdomyosarcoma , pathology , osteosarcoma , sarcoma , liposarcoma , fibrosarcoma , sarcomatoid carcinoma , renal cell carcinoma , medicine , carcinoma , biology , clear cell

Sarcomatoid component can occur in all histological subtypes of renal cell carcinoma but most commonly accompanies chromophobe renal cell carcinoma. The majority of the sarcomatoid components consist of malignant fibrous histiocytoma, fibrosarcoma or undifferentiated sarcoma areas. Heterologous differentiation in the form of osteosarcoma or rhabdomyosarcoma is very rarely encountered. We report a very rare case of a chromophobe renal cell carcinoma with osteosarcomatous differentiation that presented as a retroperitoneal mass. Renal cell carcinoma with sarcomatoid change should be always kept in mind when a retroperitoneal mass with sarcomatoid differentiation is encountered.

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