Expression of cd44 and mmp-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors | Zendy

Funda Demirağ | Zendy; Ebru Çakır | Zendy; Sibel Alpar | Zendy; İrfan Taştepe | Zendy; Sadi Kaya | Zendy

Open Access

Expression of cd44 and mmp-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors

Author(s) -

Funda Demirağ,

Ebru Çakır,

Sibel Alpar,

İrfan Taştepe,

Sadi Kaya

Publication year - 2011

Publication title -

turkish journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 14

eISSN - 1309-5730

pISSN - 1018-5615

DOI - 10.5146/tjpath.2011.01060

Subject(s) - pathology , immunostaining , cd44 , malignancy , immunohistochemistry , solitary fibrous tumor , medicine , histopathology , metastasis , biology , cancer , cell , cd34 , genetics , stem cell

Recent studies have shown that tumor cell adhesion molecules CD44 and matrix metalloproteinases (MMP-2) are expressed strongly in many tumors and associated closely with invasion and metastasis of these tumors. Although solitary fibrous tumors (SFT) have a good prognosis, a minority behave malignantly. The aim of this study was to analyze the correlation between CD44 and MMP-2 expression with histopathological parameters in SFT.

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