A NOTE ON MISSPECIFIED TRANSFORMATION MODELS | Zendy

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A NOTE ON MISSPECIFIED TRANSFORMATION MODELS

Author(s) -

Satoshi Hattori

Publication year - 2006

Publication title -

bulletin of informatics and cybernetics

Language(s) - English

Resource type - Journals

eISSN - 2435-743X

pISSN - 0286-522X

DOI - 10.5109/12601

Subject(s) - transformation (genetics) , econometrics , mathematics , statistics , biology , biochemistry , gene

The validity of the test of no treatment effect adjusting some covariates based on the misspecified transformation model, which includes the proportional odds model as a special case, is investigated. It is proven that if adjusted covariates are independent of treatment allocation, which is naturally satisfied in randomized clinical trials, and censoring mechanism is independent of the treatment allocation and covariates to adjust, the tests of no treatment effect based on the possibly misspecified transformation models are valid asymptotically. Results of a small simulation study are also demonstrated.

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