The effect of Ca-P coated bovine bone mineral on bone regeneration around dental implant in dogs

There are many obstacles to overcome in implant dentistry. The bony defect around implant can be seen in immediate installation procedures. Following tooth extraction, however, a socket often presents dimensions that may be considerably greater than the diameter of a conventional implant.1) The placement of implants in fresh extraction sockets was advocated by many authors as a means of reducing the time required for rehabilitation1)-5). Carlsson et al6). used a rabbit model and placed implants in recipient sites that provided gaps of varying size (group A = 0 mm; group B = 0.35 mm; group C = 0.85 mm) between the implant and the host bone. In biopsies obtained after 6 and 12weeks of healing it was observed that residual gaps (between 0.22 and 0.54 mm in width) occurred both in group B and C. In a recent experiment, Botticelli et al7). described a model in the dog for the study of bone reaction to implant installation and bone regeneration in marginal defects lateral to titanium rods. The authors observed that self-contained, that is, four-wall, marginal defects after a 4-month period of submerged healing were more or less fully resolved and that the newly formed bone was in direct contact with the sand-blasted, large-grit, acidetched(SLA) surface of the implant. The defects studied by Botticelli et al7). were about 5 mm deep and 1.25 mm wide, that is, larger than the size that would allow for proper hard tissue bridging, that is, the jumping distance 27),28). In a series of clinical studies8)-12), it was demonstrated that substantial hard-tissue fill could also occur in marginal defects around implants in fresh extraction sites if during