The Immunohistochemical Patterns of the β-Catenin Expression in Pilomatricoma | Zendy

Young Sik Kim | Zendy; Dong Hoon Shin | Zendy; Jong Soo Choi | Zendy; KiHong Kim | Zendy

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The Immunohistochemical Patterns of the β-Catenin Expression in Pilomatricoma

Author(s) -

Young Sik Kim,

Dong Hoon Shin,

Jong Soo Choi,

KiHong Kim

Publication year - 2010

Publication title -

annals of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.385

H-Index - 37

eISSN - 2005-3894

pISSN - 1013-9087

DOI - 10.5021/ad.2010.22.3.284

Subject(s) - pilomatricoma , immunohistochemistry , pathology , pilomatrixoma , cytoplasm , medicine , catenin , cell , beta catenin , microbiology and biotechnology , biology , wnt signaling pathway , signal transduction , genetics

Pilomatricoma is a benign follicular tumor that is composed of basaloid cells, transitional cells and shadow cells. beta-Catenin is a 92-kDa protein, and it plays important roles in cell-cell adhesion at the cell membrane and signal transduction in the nucleus. beta-Catenin has recently been shown to play an important role in the formation of hair follicle-related tumors, including pilomatricoma. However, the pattern and the intracellular localization of the beta-Catenin expression are still controversial.

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