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The Roles of Reactive Oxygen Species Produced by Contact Allergens and Irritants in Monocyte-derived Dendritic Cells
Author(s) -
Dashlkhumbe Byamba,
TaeGyun Kim,
Dong Hyun Kim,
Jeong Hwan Je,
MinGeol Lee
Publication year - 2010
Publication title -
annals of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.385
H-Index - 37
eISSN - 2005-3894
pISSN - 1013-9087
DOI - 10.5021/ad.2010.22.3.269
Subject(s) - reactive oxygen species , benzalkonium chloride , allergic contact dermatitis , cd86 , dendritic cell , immunology , contact dermatitis , irritant contact dermatitis , medicine , chemistry , immune system , biochemistry , t cell , allergy , pathology
Although reactive oxygen species (ROS) have been produced in both mouse bone marrow-derived dendritic cells (DCs) and XS-106 DCs by contact sensitizers and irritants in previous studies, the generation of ROS in human monocyte-derived DCs (MoDCs) and their role in contact hypersensitivity (CHS) has yet to be elucidated.

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