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Analysis on the Molecular Interactions between Tobramycin, an Aminoglycoside Antibiotic and Periplasmic Glucans Isolated from Pseudomonas syringae
Author(s) -
Eunae Cho,
Jae Min Choi,
Seunho Jung
Publication year - 2011
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
eISSN - 1229-5949
pISSN - 0253-2964
DOI - 10.5012/bkcs.2011.32.1.347
Subject(s) - tobramycin , periplasmic space , aminoglycoside , pseudomonas syringae , microbiology and biotechnology , pseudomonas , antibiotics , chemistry , biology , bacteria , biochemistry , gentamicin , genetics , escherichia coli , pathogen , gene
The chemical structures of these molecules are shown in Figure 1. Tobramycin (Figure 1A) consists of three rings of nebrosamine (a), 2-deoxystrapt-amine (b), and kanosamine moiety (c). Linear β-glucans (Figure 1B) are β-1,2 linked and β-1,6 branched glucans containing 6-12 glucose residues.NMR spectroscopic analysis is a technique providing the evidence of complexation

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