Isolation of an Isocoumarin and an Isobenzofuran Derivatives from a Fungicolous Isolate of Acremonium crotocinigenum | Zendy

Sang-Hee Sy Shim | Zendy

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Isolation of an Isocoumarin and an Isobenzofuran Derivatives from a Fungicolous Isolate of Acremonium crotocinigenum

Author(s) -

Sang-Hee Sy Shim

Publication year - 2008

Publication title -

bulletin of the korean chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.237

H-Index - 59

eISSN - 1229-5949

pISSN - 0253-2964

DOI - 10.5012/bkcs.2008.29.4.863

Subject(s) - isocoumarin , isobenzofuran , chemistry , chromatography , silica gel , column chromatography , fractionation , isolation (microbiology) , high performance liquid chromatography , fermentation , acremonium , microbiology and biotechnology , organic chemistry , biology , botany

(MYC-1590) wassubjected to chemical investigation. An organic extract fromcultures of this isolate showed potent antifungal activity indisk diffusion assays. Fractionation of the crude EtOAcextract of solid-substrate fermentation culture of MYC-1590by silica gel column chromatography, followed by repeatedreverse phase HPLC, afforded two new metabolites; 6,8-dimethoxy-4,5-dimethyl-3-methyleneisochroman-1-one (

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