Open AccessConcise Synthesis of Biologically Interesting Mollugin and Its Analogues
Author(s) -
Yong Rok Lee,
Xue Wang,
Yunmi Kim,
Jae Jin Shim,
Byung Nam Kim,
Do Hung Han
Publication year - 2007
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
eISSN - 1229-5949
pISSN - 0253-2964
DOI - 10.5012/bkcs.2007.28.10.1735
Subject(s) - combinatorial chemistry , chemistry
The synthesis of naturally occurring mollugin and its analogues, 3,4-dihydromollugin, cis-3,4-dihydroxy-3,4- dihydromollugin, and trans-3,4-dihydroxy-3,4-dihydromollugin was achieved starting from 1,4-dihydroxynaphthalene- 2-carboxylic acid. The key reaction is an electrocyclization for pyranyl ring formation in the presence of PhB(OH)2/AcOH.
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