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Optical Resolution of Racemic α-Hydroxycarboxylic Acids on a Dynamic Chiral Stationary Phase Derived from (S)-Leucinol by Ligand Exchange Chromatography
Author(s) -
Myung Ho Hyun,
Jung In Kim,
Yoon Jae Cho,
JaeJeong Ryoo
Publication year - 2004
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
eISSN - 1229-5949
pISSN - 0253-2964
DOI - 10.5012/bkcs.2004.25.11.1707
Subject(s) - resolution (logic) , ligand (biochemistry) , chiral stationary phase , chemistry , phase (matter) , chromatography , stationary phase , combinatorial chemistry , organic chemistry , receptor , biochemistry , computer science , artificial intelligence
Department of Chemical Education, Kyungpook National University, Daegu 702-701, KoreaReceived April 6, 2004Key Words : Dynamic chiral stationary phase, Ligand exchange chiral stationary phase, 2-Hydroxycarboxylicacid, Enantiomer separationLiquid chromatographic direct separation of the enan-tiomers on chiral stationary phases (CSPs) have beenconsidered as a most effective analytical tool for the rapidand accurate determination of enantiomeric composition ofchiral compounds.

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