Ocular Manifestations of Acute Myeloid Leukemia

A 5-year-old Infant, followed for trisomy 21 and treated for Two years for acute myeloid leukemia, has been admitted with visual disturbances and ocular swelling. The physical examination showed oculomotor paralysis, conjunctival hemorrhage, periorbital swelling and bruising (Figure 1), gingival hypertrophy was also noticed (Figure 2); A fundus examination showed Viscosity-related retinopathy with white center hemorrhage. The orbital scan performed revealed a thickening of the soft parts of the periorbital region. Figure 1: Periorbital swelling and bruising