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Type 1 reaction masquerading clinically as ENL: A Case Report
Author(s) -
Ashish Khodke,
Vanaja Shetty
Publication year - 2015
Publication title -
leprosy review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 43
eISSN - 2162-8807
pISSN - 0305-7518
DOI - 10.47276/lr.86.2.202
Subject(s) - medicine , histopathology , leprosy , lepromatous leprosy , dermatology , histology , thalidomide , pathology , surgery , multiple myeloma
Attention is drawn to a Type 1 reaction masquerading clinically as ENL. Histology showed no evidence of ENL but suggested heightened T-cell activity (CMI), a characteristic feature of Type 1 reaction. We present a case of a 29 year old man diagnosed as lepromatous leprosy with recurrent Type 2 reaction treated with thalidomide for 2 years. The patient was referred to our institute from a teaching hospital. Skin biopsies were carried out during two separate eruptive episodes 2 months apart. Histopathology showed heightened T-cell activity, but no evidence of ENL.

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