Typing of clinical isolates of Mycobacterium leprae and their distribution in Korea | Zendy

G T Chae | Zendy; SeongBeom Lee | Zendy; Taek Jin Kang | Zendy; Hang-Kye Shin | Zendy; J P Kim | Zendy; Y H Ko | Zendy; S H Kim | Zendy; N H Kim | Zendy

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Typing of clinical isolates of Mycobacterium leprae and their distribution in Korea

Author(s) -

G T Chae,

SeongBeom Lee,

Taek Jin Kang,

Hang-Kye Shin,

J P Kim,

Y H Ko,

S H Kim,

N H Kim

Publication year - 2002

Publication title -

leprosy review

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 43

eISSN - 2162-8807

pISSN - 0305-7518

DOI - 10.47276/lr.73.1.41

Subject(s) - mycobacterium leprae , tandem repeat , typing , leprosy , microbiology and biotechnology , gene , virology , biology , medicine , genetics , immunology , genome

Although there is no genetic diversity in isolates of Mycobacterium leprae, the variance of tandem repeats in the rpoT gene was recently demonstrated. We have typed clinical isolates of M. leprae in Korea using difference of the tandem repeats in the rpoT gene. Among 69 patients, 65 Korean isolates (94.2%) demonstrated four copies of the 6 bp tandem repeat (GACATC) in the rpoT gene, and incidences of three copies were found in only two Koreans and two foreigners (2.9%, respectively).

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