Open AccessRandomized Controlled Trial of Combined L-Carnitine Supplementation and Moderate-Intensity Exercises on Cardiovascular Markers and Bone Health Status in Overweight and Obese Individuals
Author(s) -
Norsuriani Samsudin,
AUTHOR_ID
Publication year - 2022
Publication title -
international journal of medical science and clinical research studies
Language(s) - English
Resource type - Journals
eISSN - 2767-8342
pISSN - 2767-8326
DOI - 10.47191/ijmscrs/v2-i2-04
Subject(s) - medicine , overweight , carnitine , body mass index , randomized controlled trial , obesity , waist , insulin resistance , body fat percentage , physical therapy , endocrinology
This article aimed to determine effects of 12 weeks of combined L-carnitine supplementation and moderate-intensity exercise on cardiovascular markers and bone health status in overweight and obese individuals. Sixty-eight participants (mean age: 29.03 ± 6.02 years old) were divided into control (C), L-carnitine supplement (S), exercise (E), combined L-carnitine and exercise (SE) groups. Participants in S and SE groups consumed 1 tablet of 1000mg L-carnitine daily. Participants in E and SE groups performed 30 minutes of brisk walking (50% HRmax), and continued with 10 to 20 minutes of Tabata exercise per session, 3 times per week. After 12 weeks of intervention, there were significant reduction in body weight (p< 0.05), body mass index (p< 0.05), fat percentage (p< 0.05), fat mass (p< 0.05), and increases fat free mass (p< 0.01) in S, E and SE groups. Regarding waist to hip ratio, blood glucose and total cholesterol, only E and SE groups showed improvements (p<0.05) and the greatest reduction was observed in SE group. No significant changes in insulin resistance in any groups. Additionally, S, E and SE groups also showed enhancement in both dominant and non-dominant radial and tibial speed of sound (p< 0.05) within and between the groups.