USE IR-SPECTROSCOPY IN TREATMENT ONCOLOGICAL PATIENTS WITH BONE METASTASES BY 153Sm-OXABIFOR | Zendy

N.P. Dikiy | Zendy; Nikolay V. Krasnoselsky | Zendy; E.P. Bereznyak | Zendy; Amos Grushka | Zendy; Елена Павловна Медведева | Zendy

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USE IR-SPECTROSCOPY IN TREATMENT ONCOLOGICAL PATIENTS WITH BONE METASTASES BY 153Sm-OXABIFOR

Author(s) -

N.P. Dikiy,

Nikolay V. Krasnoselsky,

E.P. Bereznyak,

Amos Grushka,

Елена Павловна Медведева

Publication year - 2020

Publication title -

problems of atomic science and technology

Language(s) - English

DOI - 10.46813/2020-129-046

Subject(s) - infrared spectroscopy , medicine , palliative treatment , spectroscopy , oncology , chemistry , physics , organic chemistry , quantum mechanics

Using infrared spectroscopy, we studied the character of intermolecular interactions in the samples blood plasma of oncological patients with bone metastases in the treatment of their modern β-emitter Sm-oxabifor. The therapeutic dose of the Sm-oxabifor was 1.0 mCi/kg of the patient's body weight. Analysis of the IR-spectra showed that already after the rst course of palliative radionuclide therapy there is a tendency to balance the products of free radical nature and antioxidants, which indicates the e ectiveness of the treatment. Molecular changes in the blood plasma of cancer patients with bone metastases registered using infrared spectroscopy are speci c during palliative therapy.

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