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Using infrared spectroscopy, we studied the character of intermolecular interactions in the samples blood plasma of oncological patients with bone metastases in the treatment of their modern β-emitter Sm-oxabifor. The therapeutic dose of the Sm-oxabifor was 1.0 mCi/kg of the patient's body weight. Analysis of the IR-spectra showed that already after the rst course of palliative radionuclide therapy there is a tendency to balance the products of free radical nature and antioxidants, which indicates the e ectiveness of the treatment. Molecular changes in the blood plasma of cancer patients with bone metastases registered using infrared spectroscopy are speci c during palliative therapy.

USE IR-SPECTROSCOPY IN TREATMENT ONCOLOGICAL PATIENTS WITH BONE METASTASES BY 153Sm-OXABIFOR