An independent appraisal and re-analysis of hydroxychloroquine treatment trial for COVID-19
Author(s) -
Katheron Intson,
Sachin Kumar,
Amy Botta,
Rachael Neckels,
Connie Leung,
Ali Jawaid
Publication year - 2020
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2020.20262
Subject(s) - hydroxychloroquine , medicine , covid-19 , betacoronavirus , intensive care medicine , virology , outbreak , disease , infectious disease (medical specialty)
A recent open-label study claimed that hydroxychloroquine and azithromycin represent promising new options for the treatment of SARS-CoV-2. This re-analysis reveals severe limitations in the methodology of this study, including ambiguous inclusion/exclusion of participant data and inconsistent analysis techniques, and yielded nonsignificant differences between control and treatment groups across any treatment days.
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