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Antimicrobial resistance trends in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis urinary isolates from Switzerland: retrospective analysis of data from a national surveillance network over an 8-year period (2009–2016)
Author(s) -
Veronica Zanichelli,
Angela Huttner,
Stephan Harbarth,
Andreas Kronenberg,
Benedikt Huttner,
Swiss Centre for Antibiotic Resistance ANRESIS
Publication year - 2019
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2019.20110
Subject(s) - proteus mirabilis , klebsiella pneumoniae , nitrofurantoin , fosfomycin , microbiology and biotechnology , medicine , antibiotic resistance , antibiotics , antimicrobial , escherichia coli , biology , biochemistry , gene
Swiss surveillance data confirm that resistance among uropathogenic E. coli isolates to nitrofurantoin and fosfomycin remains low. While resistance to 3rd/4th-generation cephalosporins also remains relatively low, it has been increasing and needs further surveillance. As for K. pneumoniae and P. mirabilis, high levels of susceptibility to 3rd-generation cephalosporins and quinolones were confirmed, while high prevalences of resistance to nitrofurantoin and fosfomycin discourage their use as first-line therapies for these pathogens.  .

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