Pharmacovigilance in ophthalmology in Switzerland: an analysis of the most frequently reported ocular adverse drug reactions within the last 25 years | Zendy

Julia E. Karrer | Zendy; Luis Giovani | Zendy; Gerd A. KullakUblick | Zendy; Stefan Weiler | Zendy

Open Access

Pharmacovigilance in ophthalmology in Switzerland: an analysis of the most frequently reported ocular adverse drug reactions within the last 25 years

Author(s) -

Julia E. Karrer,

Luis Giovani,

Gerd A. KullakUblick,

Stefan Weiler

Publication year - 2019

Publication title -

schweizerische medizinische wochenschrift

Language(s) - English

Resource type - Journals

ISSN - 0036-7672

DOI - 10.4414/smw.2019.20085

Subject(s) - medicine , pharmacovigilance , drug reaction , polypharmacy , adverse drug reaction , concomitant , drug , pediatrics , pharmacology

ADRs that affect the eye represented 3.5% of all pharmacovigilance reports during the reporting period. Whereas retinal haemorrhage and uveitis are known adverse reactions to angiogenesis inhibitors, the reported cases of blindness and death should heighten awareness of potential safety issues associated with VEGF inhibitors for the treatment of proliferative eye disorders.

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