Contribution of a IFN-y assay in contact tracing for tuberculosis in a low-incidence, high immigration area | Zendy

JeanPaul Janssens | Zendy; Pascale RouxLombard | Zendy; Thomas Perneger | Zendy; Marie Metzger | Zendy; Régis Vivien | Zendy; Thierry Rochat | Zendy

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Contribution of a IFN-y assay in contact tracing for tuberculosis in a low-incidence, high immigration area

Author(s) -

JeanPaul Janssens,

Pascale RouxLombard,

Thomas Perneger,

Marie Metzger,

Régis Vivien,

Thierry Rochat

Publication year - 2008

Publication title -

schweizerische medizinische wochenschrift

Language(s) - English

Resource type - Journals

ISSN - 0036-7672

DOI - 10.4414/smw.2008.12243

Subject(s) - medicine , contact tracing , incidence (geometry) , tuberculosis , kappa , latent tuberculosis , mycobacterium tuberculosis , disease , pathology , infectious disease (medical specialty) , linguistics , philosophy , physics , covid-19 , optics

o analyse, in contacts exposed to smear+/culture + (S+/C+) or S-/C+ TB, most of whom are foreign-born: 1) correlation between T-SPOT.TB IFN-gamma release assay (Oxford Immunotec, UK), TST and exposure scores; 2) agreement between T-SPOT.TB and TST in Bacillus of Calmette-Guérin (BCG) vaccinated and non-vaccinated subjects, and 3) impact of results of T-SPOT.TB on diagnosis and treatment for latent tuberculosis infection (LTBI).

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