Clinical experiences with bisphopsphonate induced osteochemonecrosis of the jaws | Zendy

Christine Dannemann | Zendy; Roger A. Zwahlen | Zendy; K W Grätz | Zendy

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Clinical experiences with bisphopsphonate induced osteochemonecrosis of the jaws

Author(s) -

Christine Dannemann,

Roger A. Zwahlen,

K W Grätz

Publication year - 2006

Publication title -

schweizerische medizinische wochenschrift

Language(s) - English

Resource type - Journals

ISSN - 0036-7672

DOI - 10.4414/smw.2006.11431

Subject(s) - medicine , osteonecrosis of the jaw , bisphosphonate , disease , bisphosphonate associated osteonecrosis of the jaw , osteoporosis , multiple myeloma , breast cancer , adjuvant therapy , surgery , cancer

Bisphosphonates are frequently used drugs in the adjuvant therapy of bone metastases and tumour-induced hypercalcaemia, but also for osteoporosis or Pagets disease. Several publications within the last three years considered osteonecrosis of the jaws to be connected with bisphosphonate therapy. Until today possible treatment strategies contain antibiotics, hyperbaric therapy and operative treatment. The tendency of healing however seems to be extremely poor. All clinicians should be aware of this new kind of side effect of bisphosphonate therapy.

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