Open AccessMatrix-bound growth factors in tissue repair
Author(s) -
Jeffrey A Hubbell
Publication year - 2006
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2006.11402
Subject(s) - extracellular matrix , morphogenesis , matrix (chemical analysis) , microbiology and biotechnology , tissue engineering , extracellular , medicine , biology , biomedical engineering , biochemistry , chemistry , chromatography , gene
Morphogenesis in tissue development and repair is guided by a variety of signals from the extracellular milieu, including growth factors that are sequestered in the extracellular matrix. Bioengineering approaches have been developed to mimic the natural interactions between growth factors and the extracellular matrix, by engineering biomolecules as novel growth factors and as novel matrix components.
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