Myocarditis: the immunologist`s view on pathogenesis and treatment | Zendy

Julia Burian | Zendy; Peter Buser | Zendy; Urs Eriksson | Zendy

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Myocarditis: the immunologist`s view on pathogenesis and treatment

Author(s) -

Julia Burian,

Peter Buser,

Urs Eriksson

Publication year - 2005

Publication title -

schweizerische medizinische wochenschrift

Language(s) - English

Resource type - Journals

ISSN - 0036-7672

DOI - 10.4414/smw.2005.10940

Subject(s) - medicine , myocarditis , immunosuppression , pathogenesis , autoimmunity , dilated cardiomyopathy , viral myocarditis , cardiomyopathy , immunology , disease , heart failure , heart transplantation , heart disease , intensive care medicine , cardiology

Viral myocarditis is a frequent and often unrecognised cause of post-inflammatory cardiomyopathy. The role of viral persistence and heart-specific autoimmunity in the development of myocarditis and heart failure is still controversial. This review updates the current view on the immunological mechanisms of disease development and addresses the current and future role of immunomodulation and immunosuppression as treatment options for defined subgroups of patients with myocarditis or dilated cardiomyopathy.

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