Monitoring of radiation-induced germline mutation in humans | Zendy

Yuri E. Dubrova | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Monitoring of radiation-induced germline mutation in humans

Author(s) -

Yuri E. Dubrova

Publication year - 2003

Publication title -

schweizerische medizinische wochenschrift

Language(s) - English

Resource type - Journals

ISSN - 0036-7672

DOI - 10.4414/smw.2003.10228

Subject(s) - minisatellite , medicine , mutation , germline mutation , genetics , germline , mutation rate , computational biology , biology , microsatellite , allele , environmental health , population , gene

Estimating the genetic hazards of radiation and other mutagens in humans depends on extrapolation from experimental systems. Recent data have shown that minisatellite loci provide a useful and sensitive experimental approach for monitoring radiation-induced mutation in humans. This review describes the progress made in validating this approach and presents the results of recent publications on the analysis of minisatellite mutation rates in the irradiated families.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research