z-logo
open-access-imgOpen Access
Thalidomide: from tragedy to promise
Author(s) -
Roger von Moos,
Rahel Stolz,
Thomas Cerny,
Silke Gillessen
Publication year - 2003
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2003.09947
Subject(s) - thalidomide , medicine , mechanism of action , drug , pharmacology , mechanism (biology) , action (physics) , immunology , multiple myeloma , biochemistry , epistemology , biology , in vitro , philosophy , physics , quantum mechanics
Thalidomide is an immunomodulatory and antiangiogenic drug. Although the exact mechanism of action is not fully understood, it has been shown to be active in a variety of diseases. There are multiple trials going on to evaluate the optimal dose of thalidomide and the importance of combining thalidomide with other drugs. This review introduces the properties and putative mechanism of action of thalidomide and summarizes the most important clinical trials with this biological modifier.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom