Functional genomics in sarcoidosis - reduced or increased apopotosis?
Author(s) -
RM Rutherford,
Jeanne Kehren,
S-D Chibout,
J J G Egan,
J J Gilmartin
Publication year - 2001
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2001.09808
Subject(s) - medicine , sarcoidosis , peripheral blood mononuclear cell , immunology , apoptosis , cancer research , biology , genetics , in vitro
A variety of studies have stressed the importance of the control of inflammatory cell longevity and the balance of pro-survival and pro-apoptotic signaling pathways. The aim of the study was to investigate the systemic activation of apoptosis pathways using cDNA array technology in patients with acute onset sarcoidosis.
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