Differentiated thyroid carcinoma
Author(s) -
E Gemsenjäger,
P U Heitz,
Burkhardt Seifert,
B Martina,
I Schweizer
Publication year - 2001
Publication title -
schweizerische medizinische wochenschrift
Language(s) - English
Resource type - Journals
ISSN - 0036-7672
DOI - 10.4414/smw.2001.09679
Subject(s) - medicine , stage (stratigraphy) , thyroid carcinoma , lymphadenectomy , thyroid , thyroidectomy , follicular phase , carcinoma , gastroenterology , follicular carcinoma , total thyroidectomy , surgery , papillary carcinoma , lymph node , paleontology , biology
The optimum treatment for differentiated thyroid carcinoma (DTC) is still debated. Results obtained using a selective treatment strategy for papillary (PTC) and follicular (FTC) thyroid carcinoma over 25 years in one institution are reported. 149 patients (mean age 46 yrs) had PTC in TNM stages I-IV in 58%, 26%, 15% and 1% respectively. Total thyroidectomy and remnant 131I ablation (43%) were carried out in TNM high-risk patients (stages III and IV) and in low-risk patients (I and II) at risk for a (curable) recurrence (stages pN1 and/or pT4). Hemi- or total thyroidectomy, without radioiodine, was used in 76% of pT1-3 N0 tumours (68%). Central and/or lateral lymphadenectomy was performed in 42% of patients (electively in the last 4 years). The mean follow-up was 7 years.
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