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A case of severe tick-borne encephalitis (TBE) 6 years after correct vaccination – could it have been prevented by a search for seroconversion after vaccination? The case described affords evidence that even after correct vaccination against tick-borne encephalitis (TBE) it is still possible to develop a severe form of TBE. The reason may be an absent or insufficient vaccine response. For persons over 50 years of age, especially those living in TBE-endemic regions and often exposed to tick bites at work or during leisure activities, it may be useful to search for seroconversion after TBE vaccination and, if there is no vaccine response, to administer one or two further vaccine doses and recommend strict prophylactic measures against tick exposure.

Schwere Frühsommermeningoencephalitis (FSME) sechs Jahre nach korrekter Impfung.