Epigenetic mechanisms of vascular dysfunction in obesity and type 2 diabetes | Zendy

Sarah Costantino | Zendy

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Epigenetic mechanisms of vascular dysfunction in obesity and type 2 diabetes

Author(s) -

Sarah Costantino

Publication year - 2019

Publication title -

cardiovascular medicine

Language(s) - English

Resource type - Journals

eISSN - 1664-204X

pISSN - 1664-2031

DOI - 10.4414/cvm.2019.02064

Subject(s) - epigenetics , epigenome , insulin resistance , type 2 diabetes , bioinformatics , dna methylation , context (archaeology) , diabetes mellitus , biology , obesity , epigenomics , medicine , disease , histone , genetics , endocrinology , gene , gene expression , paleontology

A careful assessment of the “epigenetic landscape” in cardiometabolic patients may contribute to the estimation of global cardiovascular risk, thus providing the tools for a personalised therapeutic approach. The present review describes the emerging role of epigenetics in the pathogenesis of cardiovascular complications in obesity and type 2 diabetes.

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