Cardiovascular and metabolic effects of Berberine
Author(s) -
Flora Affuso
Publication year - 2010
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v2.i4.71
Subject(s) - berberine , medicine , coptis chinensis , lipid metabolism , traditional medicine , alkaloid , disease , carbohydrate metabolism , pharmacology , traditional chinese medicine , alternative medicine , biology , botany , pathology
Berberine (BBR) is a natural alkaloid isolated from the Coptis Chinensis. While this plant has been used in Ayurvedic and Chinese medicine for more than 2500 years, interest in its effects in metabolic and cardiovascular disease has been growing in the Western world in the last decade. Many papers have been published in these years reporting beneficial effects in carbohydrate and lipid metabolism, endothelial function and the cardiovascular system. In this review, we report a detailed analysis of the scientific literature regarding this topic, describing the effects and the underlying mechanisms of BBR on carbohydrate and lipid metabolism, endothelial function and the cardiovascular system.
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