The Interaction of Clopidogrel and Proton Pump Inhibitors | Zendy

Adem Güler | Zendy; Gata Kalp | Zendy; Damar Cerrahisi | Zendy; Ad Ankara | Zendy; Zekeriya Arslan | Zendy; Gökhan Arslan | Zendy; Kalp Cerrahisi | Zendy; Klopidogrel-Proton Pompa | Zendy; İnhibitör Etkileşimi | Zendy

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The Interaction of Clopidogrel and Proton Pump Inhibitors

Author(s) -

Adem Güler,

Gata Kalp,

Damar Cerrahisi,

Ad Ankara,

Zekeriya Arslan,

Gökhan Arslan,

Kalp Cerrahisi,

Klopidogrel-Proton Pompa,

İnhibitör Etkileşimi

Publication year - 2013

Publication title -

the annals of clinical and analytical medicine

Language(s) - English

Resource type - Journals

ISSN - 2667-663X

DOI - 10.4328/jcam.771

Subject(s) - clopidogrel , medicine , proton , pharmacology , intensive care medicine , aspirin , physics , quantum mechanics

The antiplatelet agents are prescribed in acute coronary syndromes, peripheric arterial diseases, MI, and noncardioembolic stroke to decrease the atherosclerotic events and often used with proton pump inhibitors. Current studies have demonstrated considerable interaction between clopidogrel and proton pump inhibitors. PPI can lessen the effect of clopidogrel owing to the elimination of the both drugs with the cytochrom P450 isoenzymes in Liver.

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