Association of inflammation markers with epicardial adipose tissue in drug naive metabolic syndrome

DOI: 10.4328/JCAM.5734 Received: 28.01.2018 Accepted: 27.02.2018 Published Online: 08.04.2018 Printed: 01.07.2018 J Clin Anal Med 2018;9(4): 319-22 Corresponding Author: Özgür Kırbaş, Department of Cardiology, Yüksek İhtisas University, Ankara, Turkey. GSM: +905336423162 E-Mail: omerardakirbas@gmail.com Abstract The metabolic syndrome (MetS) or syndrome X is a serious health problem effecting an increasing number of person worldwide. In the present study, the aim was to investigate whether there is an association among epicardial adipose tissue thickness, insulin resistance, lymphocyte to monocyte ratio (LMR) and monocyte count-to-high density lipoprotein cholesterol ratio (MHR) levels in drug naïve patient with metabolic syndrome. Twenty-two consecutive drug-naïve women diagnosed with MetS and 30 age matched consecutive healthy women (as the control group) were recruited into the study. MHR was significantly higher [12.1 (10.5–16.4) vs 10.3 (7.0–13.8); p <0.01], whereas LMR was significantly lower in patients with MetS [ 3.6 (2.5–4.1) vs [4.1 (3.3–5.9) p = 0.02]. The present study shows that both LMR and MHR may be novel and useful indicators of MetS.