Soluble Urokinase Plasminogen Activator Receptor (suPAR) in the Diagnosis of Pulmonary Embolism

Aim: The goal of our study was to compare the suPAR levels between pulmonary embolism (PE) patients and healthy subjects and also to investigate the value of suPAR in the diagnosis of PE. Material and Method: Thirty patients diagnosed with acute PE using spiral computerized tomographic pulmonary angiography were included in the study. suPAR and D-dimer levels were measured at the time of diagnosis. Twenty-nine age- and sex-matched healthy subjects were chosen for the study. The suPARnostic ELISA Standard Kit (ViroGates A/S, Birkerød, Denmark, Code No. A001) was used for the quantitative determination of suPAR levels in plasma samples. Results: Median (95% CI) suPAR level measured in the PE group was 6.4 (6.4-10.5) ng/mL, compared to 3.3 (2.9-4.2) ng/mL in the control group (